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Obtain A Diploma Course From A Diploma Mechanical Engineering College In Gujarat

You must be aware that today the engineering colleges offer wide varieties of programs so that students are free and flexible to choose from any of them. Though the degree courses are the most common options in the field of engineering, yet many students even opt for diploma. If you are looking forward to acquiring diploma course, look into the top Diploma Mechanical Engineering College in Gujarat. Such a college will offer you wide varieties of educational programs in the same stream of engineering. Consequently, it will be easy for you to choose from any of them. You will feel glad of making such a selection.

Obtaining The Basic Technical Knowledge

When you opt for a diploma course, you can expect to get the basic technical knowledge of engineering along with scientific computing and mathematical techniques. In fact, the things that you learn from the course will certainly be helpful for you. In addition to that, it will make your way for a degree course. In fact, if you hold a diploma, acquiring admission into a college for degree program will be easier for you. This in turn will help you to delve deep into the stream of engineering.

Equivalent To Bachelor Degree Of Science

Many people often wonder whether they should go for the diploma program. Well, it might not be equivalent to bachelor degree in engineering, but it is certainly equivalent to bachelor degree of science. Therefore, if you manage to get admission into the Diploma Electrical Engineering College in Gujarat, you can be assured that the diploma program will also be recognized. Consequently, you will manage to find a job in different sectors even without completing bachelor degree program in engineering. Hence, it is up to you to make the decision and go ahead accordingly.

Check Out The Options

However, prior to making a move, it is crucial for you to acquire complete information on the course. If you are interested in civil engineering, you should acquire information on the Diploma Civil Engineering Course in India. Consequently, it will be easy for you to finalize your decision. Different colleges offer different courses and hence once you acquire a list of colleges offering diploma, you should not forget to check the courses. These courses are designed in such a way so that it enhances your overall skill and knowledge in engineering and you can come up with a bright and shining career.

I have complete information on Diploma Civil Engineering Course in India and I can offer you the necessary information in this field.

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How To Choose A Staff Augmentation Service Provider?

With great advancements in technology, more and more organizations are relying on technological solutions to solve complex problems. However, there is still a shortage of IT talent and hence, many complexities remain unresolved. As per Gartner’s prediction, about 75% of the businesses will be facing disruptions in infrastructure & operations due to shortage in technological skills by 2020. Overall, the context of doing business has become all the more complex due to multiple locations, overseas offices, short-term projects and highly specialized skill requirements.

What are the problems faced in the overall recruitment process?

Old recruitment agencies
Retention problems
Balance between speed and quality
Resources are limited
Balance between the new and traditional
Competition

Whether you are a startup looking to make your business more public or a big organization wanting to spread your business overseas, Staff Augmentation can help. How? This is something that we are going to see in this article. Here, we will be mentioning about the benefits of hiring the staff augmentation service provider, why it is necessary and how can you choose the best service provider? If you are keen in knowing about the complete process, then please continue reading ahead.

What is Staff Augmentation?

To speak about it in simple words, Staff augmentation is a flexible outsourcing strategy that enables the business people to hire tech talent globally & manage the augmented team directly. The vendors help you to hire the skilled and well-trained professionals for your project/task. You get the authority to choose from the list of candidates provided by the staff augmentation agency. So, you do not have to worry about hiring the right resources for your organization as the staff augmentation company will that for you.

So, what do you need help with?

Staff augmentation helps you find the right IT talent needed for your specific business task or project. Your service provider manages everything, right from recruitment, training & communication, but they communicate directly with your team for tighter agility and alignment.

When you are in search of a good staff augmentation partner for your business, you must start with outlining your goals: do I need support with a specific project? Do i need to meet the ongoing staffing challenges, or solutions in the given market? What kind of expertise, skills & projects do you need help with? Staff augmentation can help you with everything from hardware to the data backup & recovery, consulting and application support. By analysing your different needs and requirements, you will be able to look for a service provider who will be able to fulfill your specific requirements.

Now, when choosing a Staff augmentation service provider for your business, there are certain points that you need to consider:

The nature and type of your project
The current schedule & availability of the IT staff and
The technical details of your project

There are some other points that we must understand in detail:

Type of expertise and talent required: While there are many staffing firms out there in the market who offer a varied range of talents they can provide, it is always smart to go for an organization that specializes in a specific type of talent. Focusing on a particular industry hones a staffing organization’s ability to discern the deeper requirements of the companies in that niche and select the best individuals that fit the criteria. This removes job mismatch and the hassle of replacing them with someone more fit for the role.

For instance, if you are looking for individuals with technical expertise, it is always a great idea to look for renowned and reputed IT staffing agencies since they know best what IT individuals must be like in terms of required expertise and skills.

Transparency: The primary requirement for a strong relationship between you and the staff augmentation partner is based on absolute transparency and clear communication. It means that the staffing agency should be able to provide you with a well-defined documentation on what its exact role is and a complete transparent break-down of costs.

They should also be able to reply to your questions in such a way that they clear all your doubts on a high-level with minimal knowledge of existing hiring processes. This helps engender trust & set realistic expectations.

Are their contracts one-size-fits-all?: Organizations usually find that the staff augmentation providers have a single approach towards doing business. Every deal follows just one specific template, and one-size-fits-all types of solutions. Yet, the reality is that every organization, every project and every job requisition is very unique. Look for a solutions provider that is willing to get creative, deliver what you need and develop a customized scope of work. In most of the cases, a one-size-fits-all solution is not going to offer you the results, flexibility, or savings that make staff augmentation attractive in the first place. The right kind of provider will work with you, your immediate requirements, and then support you as the business grows and your requirements evolve.

Add-on Solutions: Every staff augmentation service provider has a unique set of value-added services that they provide as an add-on or as part of their standard package. These solutions may include, providing specialized training to the recruits processed or conducting skills testing prior to onboarding.

It is crucial to check for these solutions to maximize the advantage your company gets from your staff augmentation partner.

Will they be able to meet your deadlines: You must also make sure that the staff augmentation agencies you talk with can meet your given timelines. How fast & agile is their execution? Waiting 60 days to fill a primary role, for example, is just not cost effective. Staff augmentation must enable you to move your projects forward quickly. There are many ways to evaluate. What does their network look like? How long do they quote a resolution? How are they into handling internal discussions around process changes or new business opportunities? Does the speed of communication at this stage reflect the speed you require? Choose efficient, customer-focused and agile partner that delivers results at the speed your company’s demands.

Conclusion

You must hire an agency or a firm that is able to meet the requirements and needs of your business with the right kind of resources and talent.

You must select a service provider that can help you overcome the disadvantages of the staff augmentation model. A great service provider can give you access to many of the skill sets and flexible workers who stay true with the contract.

They must also be able to provide project management services. They must also have a proper platform for communication between you and the augmented staff.

Make sure to read the reviews provided and check the ratings on renowned platforms like Glassdoor, Clutch and SoftwarFirms before hiring any Staff augmentation service provider. This way you will get to know more about them and won’t face any problem in the future.

If you have any queries or suggestions, please feel free to mention them below in the comment box. We will be happy to discuss them with you.

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Novel Biomarkers Help to Predict Rejection after Stem Cell Transplantation Found

The latest study by Dr. Sophie Paczesny and others at MUSC Hollings Cancer Center revealed a new class of immune cell biomarkers, which may reveal which patients are most at risk of graft-versus-host disease (GVHD). This study was published on Science Translational Medicine.

Paczesny, director of the Department of Microbiology and Immunology at MUSC, explained: “Allogeneic HSCT remains the only effective therapy for leukemia. In HSCT, donor-matched cells are injected into the blood of diseased patients and eventually enter the bone marrow. Some of these cells differentiate into immune cells that help eliminate residual leukemia cancer cells that are not killed by chemotherapy. However, some donors’ immune cells may attack the patient’s own healthy tissue at the same time, which is called graft-versus-host disease.”

GVHD affects up to 50% of patients undergoing HSCT and can manifest in multiple organs. About one-third of people with GVHD experience localized effects in the gastrointestinal tract (GI-GVHD), posing the highest risk of death.

This phenomenon was further described by Paczesny. “For leukemia patients, the donor cells you provide have different biological or antigenic characteristics than the recipients. This is how these immune cells recognize leukemia and destroy leukemia. However, these antigens are also present in normal tissues especially in body regions with the most microbiota (such as the gut). Therefore, donor immune cells flare up there and symptoms are most difficult to treat.”

Bone marrow stem cells are called pluripotent stem cells, which means that they can mature into many different types of cells. This includes red and white blood cells and other immune cell types responsible for balancing immunity and tolerance, such as dendritic cells and T cells.

Dendritic cells are able to exchange information with T cells through antigen molecules presented by MHC complexes on the cell surface. T cells are activated in recognition of “non-self” antigens and then play a key role in triggering the body’s other defense systems against foreign invaders, which may include transplanted cells from different hosts.

Previous work from the Paczesny laboratory has shown that immune cell signaling pathways in GI-GVHD increase the number of “hyperactivated” pathogenic T cells (Th17 cells) in the blood of these patients. The presence of these aggressive T cells was associated with lower survival compared to patients lacking GVHD or with milder forms of GVHD in the skin. These cells are also unique in their ability to induce ICOS, a class of T cell signaling coreceptors.

Paczesny said. “We are trying to understand where the activation of these T cells comes from. What antigen-presenting cells are?”

Since ICOS ligands are located on the surface of antigen-presenting cells, such as dendritic cells, they can be easily detected using existing technologies, such as flow cytometry, which can scan the blood for external labeling on cells. In this way, individuals who develop GI-GVHD symptoms after treatment may be flagged out.

Paczesny’s group showed that GI-GVHD patients had increased levels of dendritic cells expressing ICOS ligands (specifically a population called plasmacytoid dendritic cells) compared to controls. Crucially, patients with high levels of these cells had a much lower three-year survival compared to low levels of cells.

Dr. Djamilatou Adom, a postdoctoral researcher working with Paczesny, further investigated the role of ICOS signaling using mice in GI-GVHD. First, they showed that genetic abrogation of ICOS ligand production before transplantation of donor mouse bone marrow cells into recipient mice could protect recipient mice from GvHD related death. In addition, the researchers used “humanized” mice with a non-functional immune system and found that transplanting plasmacytoid dendritic cells expressing human ICOS ligands into these mice (whose own bone marrow has been destroyed by radiation) resulted in increased levels of Th17 cells within GVHD.

The involvement of plasmacytoid dendritic cells (pDCs) in GVHD is an interesting finding, Paczesny says. “If these cells are not stimulated, they are generally considered to be tolerogenic. In other words, they can reduce the severity of GVHD. However, if they activate T cells, for example by binding ICOS activation, they become more toxic and may drive the development of GVHD.”

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